Amenorrhea - absence of a menses within 6 months and more in the age of 16-45 years. As the physiological phenomenon is observed at this age during pregnancy and a lactemia. A pathological amenorrhea - a sign of organic or functional disturbances at any level of genesial system; it is accompanied by sterility. Allocate a primary and secondary pathological amenorrhea.

Primary amenorrhea - a pathological condition at which there was no menses. On a level of a lesion of genesial system a primary amenorrhea conditionally divide on subthalamic, adrenal and uterine. It is practically important to distinguish a primary amenorrhea at absence of puberty, at a delay of puberty, on a background of virilescence and at a normal female phenotype that allows to assume a level of a lesion of genesial system. The primary amenorrhea at absence of puberty is bound to a dysgenesis of gonads - their deep underdevelopment caused by a pathology of sexual chromosomes. The primary amenorrhea at a delay of puberty usually has a cerebral genesis. At an organic pathology of a brain (a tumour, consequences of a trauma, an intoxication, an infection) on the foreground acts the expressed psychological symptomatology, in occasion of which patient are surveyed and treated at psychiatrists and neuropathologists. The amenorrhea on a background of a delay of puberty can be consequence of functional disturbances of a zone of the hypothalamus, shown insufficient formation, a subthalamic hypogonadism, and pathological processes in a forward share of a pituitary body, for example congenital absence of secretion of gonadotrophic hormones. Patients have an intersexual body build, at them mammary glands, a sexual pilosis poor are underdeveloped. The hypoplasia of external and internal genitals is characteristic.