Cardiomyopathies - primary noninflammatory lesions of a myocardium of the obscure etiology (idiopathic), not bound to valval defects or endocardiac shunts, an arterial or pulmonary hypertensia, ischemic illness of heart or general diseases (diffusive diseases of a connecting tissue, an amyloidosis, a hemochromatosis, etc.).
The pathogenesis of a cardiomyopathy is obscure. Participation of genetic factors, ferment and endocrine disturbances Is supposed, the role of a virus infection and immunologic shifts is not excluded.
The hypertrophic cardiomyopathy is characterized by a hypertrophy of walls and decrease of volume of a cavity of a left ventricle, normal or its strengthened contractility and disturbance of a relaxation (diastolic dysfunction).
