Colitis nonspecific ulcerative - the widespread canker of a mucosa of a colon, since a straight line, described fixing current and accompanied serious local and systemic complications. The etiology is obscure. There are bases to consider this disease by autoimmune process which is accompanied by allergic and banal infectious lesions. Plural ulcers of a mucosa of a colon merging among themselves lead to the expressed intoxication, sharp disturbances of metabolic processes and septicopyemic lesions skins (pyoderma), an eye (iridocyclites), joints (a purulent arthritis), a liver, etc. often meeting attribute of a nonspecific ulcerative colitis pseudopolypuses (inflammatory polyps), representing growths of a tissue, more often at edge of ulcers single or merging among themselves are. Owing to a hyperpermeability of the wall of an intestine amazed by ulcerative process and it is immediate as a result of perforations of ulcers there is a local circumscribed or diffuse peritonitis.

Signs, current. Disease can begin was acutely or in the form of primarily-chronic process.

The clinical picture includes a triad of the main attributes: diarrhea, allocation of a blood with a feces and abdominal pains. In the beginning usually there is a liquid chair with an impurity of slime and a blood and the general delicacy. Diarrhea can progress (20-30 times day) and to lead to a deaquation, an attrition, a sharp anemia, disturbance of an electrolytic exchange with a convulsive syndrome. Temperature subfebrile, the expressed shifts of inflammatory character in the given laboratory researches accrue. The boring of a peritoneum, an abdominal distention (an acute toxic dilatation of an intestine), systemic lesions can be observed. Distinguish lightning, acute, chronic recurring and constant (torpid) forms of current of disease. The lightning form proceeds some days and often comes to an end with mors because of development of complications (perforation, a bleeding, a toxic dilatation). Acute, chronic relapsing and torpid forms differentiate on gravity of displays, they can be accompanied by various local and systemic complications which happen dangerous to a life (a peritonitis, a septicopyemia, a deep anemia and a dystrophia). Other, less expressed complications can independently or under influence of treatment to remit, and disease passes in a stage of remission with a high probability of an exacerbation at stressful situations or during the spring and autumn periods of year.