Dysbacteriosis intestinal - a syndrome, described superfluous microbial dissemination of a small bowel and change of microbial structure of a colon. If at healthy people in a small bowel and in a colon bacteria, anaerobic streptococcuses prevail, E. coli, enterococci and other microorganisms at a dysbacteriosis equilibrium between these microorganisms is broken, the putrefactive or fermentative flora, mushrooms, mainly type Candida plentifully develops, in an intestine microorganisms, in norm uncharacteristic for it are found out, a plenty of microbes is in contents of proximal departments of a small bowel and in a stomach. The is conditional-pathogenic microorganisms which are usually found out in contents of an intestine in small amounts, instead of nonpathogenic strains of an intestinal rod activly develop, its more pathogenic strains are quite often found out. Thus, at a dysbacteriosis qualitative and quantitative changes of structure of microbial associations in a gastrointestinal tract (the microbial landscape varies) are observed.

Etiology, pathogenesis. In an intestinal dysbacteriosis result the diseases of a stomach proceeding with an achlorhydria (a chronic gastritis), an intestine (a chronic enteritis, a colitis), a pancreas, a liver, kidneys, malignant neoplasms, a resection of a stomach and a duodenum, disturbance of a peristalsis. The reason of an intestinal dysbacteriosis can be long, uncontrollable reception of antibiotics, especially wide spectrum of the action, overwhelming normal intestinal flora and those microorganisms promoting development which have fastness to these antibiotics, and also application of glucocorticoids. Thus, a dysbacteriosis - display or one of complications of a basic disease, but not the independent nosological form. At a dysbacteriosis opposing activity of a microflora of an intestine concerning pathogenic and putrefactive microorganisms is broken. Products of abnormal splitting of alimentary substances unusual to an intestine a microflora (organic acids, aldehydes, a skatole, a hydrogen sulfide, etc.), formed in lots, irritate a wall of an intestine. Influence of microbial toxins on structure and activity of membranous enzymes causes disturbance of membranous digestion in a small bowel, stimulation of secretion of water by them and electrolytes enterocytes - to a secretory diarrhea, premature deconjugation of cholic acids in an intestine - to disturbance of an absorption of Adepses, a steatorrhea.

Signs, current. Signs of a dyspepsia, depression of the appetite, unpleasant taste in a mouth, a nausea, a meteorism, diarrhea or constipations are characteristic. Fecal masses have a sharp putrefactive or acidic smell. Attributes of the general intoxication are often observed, the flaccidity is observed, the working capacity decreases.