Glomerulonephritis - an infectious disease-allergic of kidneys.
Etiology, pathogenesis. Development of a diffusive glomerulonephritis is bound to acute and chronic diseases mainly the streptococcal nature. The streptococcal infection at a normal immunologic reactivity of the child causes an acute diffusive glomerulonephritis (acute, cyclic disease). Partial defects of immune systems frame conditions for formation of a chronic glomerulonephritis (fixing, wavy disease) which is bound to the circulating immune complexes fixed on glomerular membranes more often. Less often the lesion of glomuluses is caused by formation of specific antibodies to basal membranes. The so-called fabric hypoplastic dysplasia, that is backlog of development of a renal tissue can serve in kidneys from chronological age of the child to one of factors of synchronization of inflammatory process.
Clinical picture. The acute diffusive glomerulonephritis in the beginning is shown by the general delicacy, a headache, a nausea, a back pain, a chilling, depression of appetite. Are marked paleness of the face, the quantity of the allocated urine sharply decreases, however its relative density remains high. Urine gets color of meat slops. In cases of a microhematuria color wet can not vary.
Edemas settle down usually on the face, appear in the morning, by the evening decrease. Before development of visible edemas about 2-3 litres of a liquid can be late in muscles, a hypodermic fat.
The lesion of cardiovascular system at acute current of a glomerulonephritis is marked at 80-85 % of children. The hypertensia meets less often, than at adults, keeps not for long and to the extremity of 2-3 weeks disappears.
