Hemochromatosis (a pigmental cirrhosis of a liver, bronze Diabetum, a siderophilia, etc.) - the general disease, described disturbance of an exchange of iron, its raised maintenance in Serum of a blood and accumulation in tissues and internal organs. Meets rather seldom, mainly at men.

Etiology, pathogenesis. A primary (idiopathic) hemochromatosis survey as congenital disease at which in a thin intestine of the person much more gland, than in norm is soaked up, and it is superfluous is deposited in tissues - in a liver, a pancreas, a myocardium, a skin and so on. There is a secondary is inflammatory - sclerous reaction of tissues of the amazed organs. In unstriated muscles also it is superfluous the lipofuscin, in a false skin - a melanin is postponed. The secondary hemochromatosis arises at superfluous entering in an organism of iron (long uncontrollable treatment by iron preparations, at repeated frequent hemotransfusions, etc.).

Signs, current. The gray-brown or brownish color, the enlarged both dense liver and a diabetes mellitis (more often - achrestic) are characteristic a hyperpegmentation of a skin (especially open parts of a body, axillary hollows, palms, genitals and old dermal cicatrixes), accepting.