Hepatoses - illnesses of the liver, its parenchyma described by dystrophic changes without the expressed is mesenchymal-cellular reaction. Depending on the nature of disturbance of a metabolism distinguish fatty and pigmental hepatoses. The fatty hepatosis (a fatty dystrophia, fatty infiltration, a steatosis of a liver) is characterized fatty (sometimes with elements albuminous) a dystrophia of hepatocytes and chronic current.
Etiology, pathogenesis: Principal causes of development of a fatty hepatosis - an alcoholism, less often an obesity, a diabetes mellitis, other endocrine frustration (a myxedema, a thyrotoxicosis, an acromegalia), deficiency of fiber and vitamins, diseases of organs of the digestion, absorptions accompanied by disturbances (a chronic pancreatitis, a ulcerative colitis, etc.), chronic intoxications four-chloride Carboneum, phosphoric organic bonds, other toxic substances possessing hepatotropic action, bacteriemic toxins, etc.
The pathogenesis of a lesion of a liver in these cases basically is reduced to disturbance of a metabolism of lipids in hepatocytes and formations of lipoproteins.
Signs, current. The form with small signs is possible, at which the clinic masks displays of a basic disease (a thyrotoxicosis, a diabetes mellitis, etc.), a toxic lesion of other organs or accompanying diseases of a gastrointestinal tract. In other cases the expressed phenomena of a dyspepsia, the general delicacy, a dull ache in right hypochondrium are observed; sometimes - an easy icterus.
