The neuroarthritic diathesis is characterized by genetically determined disturbances of function of some the enzymes which are taking part a purine exchange and synthesis of a urinary acid. Meets approximately at 0,5-3 % of children. Thus instability of a carbohydrate and lipide exchange is marked. The last basically is bound to dropping activity of processes of acetylation in a liver. The hyperuricemia raises excitability of nervous system, strengthens sensitivity of a wall of vessels to action of catecholamins, diabetogenic an effect has, promotes a lithogenesis in kidneys.
Children with a neuroarthritic diathesis are whimsical, erethitic, a subnutrition, but are predisposed to an obesity in advanced age. At them hyperkinesias, logoneuroses, night pavors, affective cramps, bad appetite, a smell of an acetone from a mouth and from urine, attacks of a vomiting, rising of arterial pressure can be marked.
