Sarcoidosis - a general disease of the obscure etiology, described by formation in tissues of the granulomas consisting of epithelial cells and individual huge cells or type alien ph. of the Granuloma are same, spherical, precisely differentiated from. A surrounding tissue. Unlike tubercular eminences in them there is no caseous necrosis. The sarcoidosis meets mainly in young and middle age, a little bit more often at women. Organs, mainly lymph nodes, easy, a liver, a lien, less often than a kidney are amazed practically all, the skin, eyes, bones, etc. is most often marked a lesion of organs of respiration.

Signs, current. Stage I is characterized by augmentation of intrathoracic lymph nodes. At II stage alongside with it the expressed intersticial changes and the centers of various size mainly in average and bottom departments of lungs are defined. In III stage are taped an appreciable diffusive fibrosis in lungs and large, usually confluent focuses, and also the expressed emphysema quite often with violent dystrophic cavities and pleural inspissations. Approximately 1/3 patients at I and II stages do not have appreciable subjective frustration and illness is taped at fluorographic research. Current subacute or chronic, quite often wavy; delicacy, a subfebrile condition, a stethalgia, dry tussis, depression of appetite are marked. Rhonchuses in lungs are listened seldom and in a small amount. Sometimes the sarcoidosis begins was acutely with a heat, a swelling of joints of extremities, occurrences of a nodulose erythema, mainly on a skin of anticnemions, augmentations of external lymph nodes. In a blood - bent to a lymphopenia and a monocytosis, less often an eosinophilia. A characteristic attribute - depression of the general and local sensitivity to a tuberculin, in this connection a Mantoux reaction usually negative. A homogenate of a tissue of the amazed lymph node enter subcutaneously, in a month in a place of introduction granulomas (now assay is used seldom) are formed. At III stage of disease these attributes are expressed in a greater degree, the dyspnea and a cyanosis gradually accrue. Duration of illness from several months about many years.