Sepsis of newborns. Not full-term children are most subject to disease.

Etiology, pathogenesis. The originator are various pathogenic and is conditional-pathogenic microorganisms (a staphilococcus, a salmonella, E. coli, etc.). A greater role acute and chronic infectious diseases at mother play, various obstetric interventions, the long anhydrous period, an endometritis, presence of other pyoinflammatory centers at mother (a purulent mastitis, etc.) . Contributing factors are the fetal hypoxia, an intracranial birth trauma, a dismaturity of the newborn, damage of a skin of the newborn during obstetric operations and such manipulations as an intubation, the catheterization of subclavial and umbilical veins, etc. the Greater role in generalization of process belongs to a virus infection. Entrance hiluses happen a surface on a skin, mucosas, a umbilical wound and umbilical vessels, and also the intact skin and mucosas of the top respiratory ways, a gastrointestinal tract is more often. At a fetal sepsis the center of an infection is usually localized in a placenta or any organ of the pregnant woman. Quite often entrance hiluses and the primary septic center to define it is not possible.

Process can proceed as a hematosepsis (basically at not full-term, weakened full-term) or septicopyemias. The hematosepsis is characterized by an intoxication of an organism without the local purulent inflammatory centers while at a septicopyemia the centers (abscesses, phlegmons, an osteomyelitis, pneumonias of destructive type with pleural complications, a purulent meningitis, an otitis, etc.) are taped.